• Domaine : Masters du domaine SCIENCES, TECHNOLOGIES, SANTE
  • Diplôme : Master
  • Mention : Biologie moléculaire et cellulaire
  • Parcours : Leading international vaccinology education (ERASMUS+)
  • Unité d'enseignement : Immunodeficiencies
Nombre de crédits de l'UE : 3
Code APOGEE : BIO1301M
UE Obligatoire pour ce parcours
UE valable pour le semestre 1 de ce parcours
    Responsabilité de l'UE :
DELPRAT CHRISTINE
 christine.delpratuniv-lyon1.fr
04.72.68.19.54
    Type d'enseignement
Nb heures *
Cours Magistraux (CM)
20 h
Travaux Dirigés (TD)
10 h
Travaux Pratiques (TP)
0 h
Total du volume horaire
30 h
* Ces horaires sont donnés à titre indicatif.
    Programme - Contenu de l'UE :
Universitat Autònoma de BarcelonaHERNÁNDEZ, Manuel, Associate Professor Immunology, HVHde la CALLE, Óscar, Associate Professor Immunology, HSP

Contact: Oscar de la CALLE-MARTIN, Associate Professor Immunology
e-mail: odelacalle@santpau.cat
Manuel HERNÁNDEZ GONZÁLEZ, Associate Professor Immunology
e-mail: manhernandez@vhebron.nete
Keywords: Primary and secondary Immunodeficiencies; innate immunity deficiencies, adaptive immunity deficiencies, diseases of immune dysregulation, acquired immunodeficiency syndrome 

Aims of “Immunodeficiencies”:

 1. Understand the main mechanisms of immunodeficiency diseases;

2. Be familiar with the main types of therapy applied to immunodeficiency diseases;

 3. Know the laboratory tools for immunodeficiency diseases' diagnostic;

4. Understand the limitations, risks and diagnostic use of vaccines in immunodeficient individuals

Programme

1. Primary Immunodeficiencies (PID) definition, classification and epidemiology

2. Molecular basis of the PIDs. Present and future

3. Combined Immunodeficiencies. Treatment: hematopoietic stem cell transplantation, gene therapy

4. Predominantly antibody deficiencies. Treatment with immunoglobulins

5. Diseases of immune dysregulation. Familial hemophagocytic lymphohistiocytosis and PID syndromes with autoimmunity; 6. Complement deficiencies; 7. Congenital defects of phagocytes

8. Defects in innate immunity; 9. Advanced research techniques in primary immunodeficiencies diseases; 10. Acquired Immunodeficiency Syndrome 

Speakers: Immunology Teaching Staff and clinicians from two of the UAB major Hospitals: Hospital de la Vall d'Hebron and Hospital de Sant Pau and other clinical centres. The tutorials will involve work by the students under the guidance of the different tutors 

Learning outcomes:
After the course students will be able to use immunopathology reasoning to understand clinical cases of immunodeficiency; know which immunology tests can help in the diagnosis of the main immunodeficiency diseases; have the capability to discuss research results at a journal club or at a research meeting; know what they can expect from vaccination to immunodeficient individuals.

Updated on April 9, 2019

    Modalités de contrôle des connaissances et Compétences 2018-2019 :
TypeLibelléNatureCoef. 
CTContrôle TerminalCT : ImmunodeficienciesEcrit session 1 / Ecrit session 23
    Liste des autres Parcours / Spécialité / Filière / Option utilisant cette UE :
Date de la dernière mise-à-jour : 09/04/2019
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