- Unité d'enseignement : Advanced and green methods in the chemistry of C=C bonds
Nombre de crédits de l'UE : 3
Code APOGEE : CHM2249M
Type d'enseignement
Nb heures *
Cours Magistraux (CM)
18 h
* Ces horaires sont donnés à titre indicatif.
Pré-requis :
M1 Master Chimie - spécialisation "Synthèse Organique et chimie des Molécules Bioactives" ou Equivalent
Compétences attestées (transversales, spécifiques) :
Acquired Skills: a working knowledge of modern synthetic methods in the chemistry of C=C Π bonds, a knowledge of the major transition state models used to predict the stereochemical outcome of asymmetric reactions, and the ability to read and understand the reactions, selectivities and specificities, and retrosynthetic strategy of the total synthesis of a complex natural product
Programme de l'UE / Thématiques abordées :
To provide an overview of advanced methods of modern synthetic chemistry, focusing here on the chemistry of C=C Π bonds, as well as of the current efforts at developing sustainable alternatives.
Starting with some of the classical reactions from the undergraduate program, we will provide modern variants, asymmetric versions (with an overview of the major transition state models), “greener” methods, and examples in total synthesis.
The Diels Alder reaction
• Advanced methods
• Asymmetric versions (rel. diastereoselection, induction, “enantioselective” versions)
• Sustainable methods
• Total synthesis [3+2] Dipolar Cycloaddition reactions
• The Suzuki reaction
• The Olefin Metathesis reaction
• Directed metallation reactions
• Radical cyclisation reactions
• Photochemical processes : Photon as a green reagent
• Applications in natural product synthesis
Parcours / Spécialité / Filière / Option utilisant cette UE :
Date de la dernière mise-à-jour : 31/08/2017
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